Predicting toxicity

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Predicting dietborne metal toxicity from metal influxes.

Dietborne metal uptake prevails for many species in nature. However, the links between dietary metal exposure and toxicity are not well understood. Sources of uncertainty include the lack of suitable tracers to quantify exposure for metals such as copper, the difficulty to assess dietary processes such as food ingestion rate, and the complexity to link metal bioaccumulation and effects. We char...

متن کامل

Predicting toxicity through computers: a changing world

The computational approaches used to predict toxicity are evolving rapidly, a process hastened on by the emergence of new ways of describing chemical information. Although this trend offers many opportunities, new regulations, such as the European Community's 'Registration, Evaluation, Authorization and Restriction of Chemicals' (REACH), demand that models be ever more robust. In this commentar...

متن کامل

Predicting the toxicity of chromium in sediments.

Chromium exists in sediments in two oxidation states: Cr(III), which is relatively insoluble and nontoxic, and Cr(VI), which is much more soluble and toxic. Chromium(VI) is thermodynamically unstable in anoxic sediments, and acid-volatile sulfide (AVS) is formed only in anoxic sediments; therefore sediments with measurable AVS concentrations should not contain toxic Cr(VI). If this hypothesis h...

متن کامل

Predicting Toxicity in Marine Sedimen'ts with Numerical Sediment Quality Guidelines

.Abstract-Mat~hing'syno~tically collected chemical and laboratory bioassay data (n = 1.068) were compiled from analyses of surficial sediment samples collecred during 1990 to 1993 to evaluate the predictive ability of sediment quality guidelines (SQGs). specifically, effects range-low (ERL). effects range-median (ERM). threshold effects level (TELL and probable eifects level (PEL) values. Dam w...

متن کامل

Towards Predicting Their Toxicity and Physico-Chemical Properties

Nanomaterials are becoming an important component of the modern life and have been the subject of increasing number of investigations involving various areas of natural sciences and technology. However, theoretical modeling of physicochemical and biological activity of these species is still very scarce. The prediction of the properties and activities of ‘classical’ substances via correlating w...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Nature Reviews Drug Discovery

سال: 2007

ISSN: 1474-1776,1474-1784

DOI: 10.1038/nrd2470